Christopher P. Weis, Ph.D., D.A.B.T.
Toxicologist | Environmental Health Scientist | Public Health Leader
Bethesda, Maryland·[email protected]
Toxicologist with more than 35 years of experience across federal science policy, forensic investigation, and emergency response, spanning toxicology, biophysics, chemistry, and comparative physiology. Expert in collecting, interpreting, and applying exposure, toxicological, and risk-assessment data to chronic exposure cases, environmental emergencies, and federal environmental disasters, including human health risks from chemical, biological, and radiological hazards. Former Senior Toxicology Advisor to the Director of NIEHS and senior Co-Chair of the White House OSTP Subcommittee on Toxics and Risks (2010–2016); past President of the American Board of Toxicology. Experienced in leading multidisciplinary science teams, managing multimillion-dollar research and contract portfolios, communicating risk to the public and media, and translating evidence into policy alongside EPA, FDA, WHO, UNEP, and state agencies.
Professional Experience
Science Director and Principal
2022 – PresentWeis Toxicology, LLC — Bethesda, MD
- Advise clients on public health, emergency response, and occupational hazard assessment, grounded in exposure science, toxicology, and medical physiology.
- Analyze acute and chronic health risks and design practical, evidence-based mitigation strategies for complex exposure scenarios.
- Provide risk communication and expert scientific support in regulatory, occupational, and litigation settings.
Toxicology Liaison and Senior Advisor, Office of the Director
2010 – 2021NIH / NIEHS and National Toxicology Program — Bethesda, MD
- Senior Co-Chair, White House OSTP Subcommittee on Toxics and Risks (2010–2016), Committee on Environment, Natural Resources and Sustainability.
- Helped conceive, organize, and implement the WHO Chemical Risk Assessment Network, now more than 70 public health institutions across 50-plus countries.
- Represented the Director in policy and scientific decision-making meetings across federal agencies and at scientific conferences; served as NIEHS/NTP designated representative on national and international committees, task forces, and working groups.
- Led outreach and coordination with CDC/NIOSH, FDA, NCI, USDA, ATSDR/NCEH, OSHA, CPSC, and EPA, and with industry, labor, advocacy groups, and the broader NTP community.
- Supplied environmental toxicology expertise for program plans, annual plans, briefing papers, and congressional testimony.
Senior Forensic Toxicologist / Advisor to the Director
2002 – 2010U.S. EPA, National Enforcement Investigations Center — Denver, CO
- Led and managed investigations of complex exposure sources critical to national health protection, designing toxicological studies with standard and emergent forensic methods to link human health effects to specific poisons, mixtures, and their sources.
- Directed interdisciplinary enforcement teams — engineers, physicians, epidemiologists, chemists, microscopists, and technicians — through team leaders.
- Defended federal investigations in dozens of federal court cases and advised DOJ, U.S. Attorneys, Congress, EPA, and state agencies on the science and policy of environmental enforcement.
- Developed hazardous-substance attribution methods with federal and academic scientists; mentored graduate students in toxicology and environmental science.
Senior Toxicologist / National Advisor
1993 – 2002U.S. EPA Region 8 — Denver, CO
- Science Support Coordinator for EPA during the Capitol Hill anthrax incident: designed sampling plans for the Hart Senate Office Building and led scientists, physicians, hygienists, laboratory staff, architects, and air specialists in exposure assessments that protected cleanup crews and confirmed decontamination of Senate offices.
- Set emergency remediation standards for the mass-casualty asbestos response in northwestern Montana — the most severe residential man-made environmental disaster in the United States — identifying and mitigating deadly community exposures.
- Served as National Advisor on toxicology and environmental risk evaluation for more than 50 Superfund actions, including Rocky Mountain Arsenal (CO) and Clark Fork River (MT).
- Initiated, organized, and funded an EPA–U.S. Public Health Service interagency agreement for rapid on-site exposure characterization and risk assessment across six states, responding to major environmental incidents nationwide.
- Managed more than $2 million in contracts annually plus a staff of toxicologists and environmental professionals; ran GLP-compliant exposure research programs; conducted rapid risk assessments during emergencies including Hurricanes Katrina and Rita.
- Developed guidance for data acquisition, interpretation, and risk assessment; represented the Agency to the public, media, and legal and regulatory forums.
Adjunct Professor, Department of Pharmaceutical Sciences
1999 – 2020University of Colorado Health Sciences Center — Denver, CO
- Taught applied toxicology, regulatory toxicology, and environmental forensics to Skaggs School of Pharmacy students, occupational medicine fellows, and toxicology graduate students; collaborated on research with University of Colorado and Colorado State University scientists.
Regional Toxicologist
1989 – 1993U.S. EPA Region 8 — Denver, CO
- Served as federal risk assessment representative for more than 50 Superfund actions across six Rocky Mountain and Plains states, including Rocky Mountain Arsenal, the Clark Fork sites, and Leadville, CO; quantified childhood lead poisoning at major western lead sites, enabling EPA actions that reduced blood lead levels in thousands of children.
- Interpreted complex exposure and health science data to guide regional and national policy; advised senior management, federal agencies, and the public on toxicological, biochemical, epidemiological, and pharmacological questions.
- Managed science support for emergency and non-emergency response, and a research budget for toxicology and risk assessment studies conducted under federal quality assurance guidelines.
Earlier Research & Teaching Appointments
NIH Postdoctoral Fellow, University of Virginia, Molecular Physiology and Biophysics (1987–1989) — investigated calcium ion transport across membranes and the Ca2+-transporting ATPase of cardiac and skeletal muscle sarcoplasmic reticulum using radiotracer, immunological, molecular biology, and spectroscopic methods (time-resolved fluorescence, EPR, NMR).
Research Associate, Michigan State University, College of Veterinary Medicine and Pesticide Research Center (1984–1987) — biophysical and toxicological studies of heavy metals and pesticides on cellular membranes and signaling; results published in international journals and presented at Biophysical Society meetings.
Physiology Faculty, Michigan State University College of Osteopathic Medicine, Medical Access Support Program (1985–1986) — taught intensive summer courses in physical chemistry, cellular physiology, and electrophysiology for first-year medical students.